We are interested in conducting research that will benefit the people of West Virginia. The application of what we learn from research is vital to the improvement of the health, quality of service, and patient care throughout West Virginia. Vandalia Health Charleston Area Medical Center is dedicated to providing the latest in new therapies and applications.

See below for a categorized listing of clinical trials currently underway at CAMC. You can also view all clinical trials.

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The PROACTIVE-HF-2 Trial is a research study looking at a small device called the Cordella™ Pulmonary Artery Sensor. Doctors use this sensor to check how your heart is working by measuring the pressure in your lungs every day. The goal of the study is to help people with heart failure feel better and stay out of the hospital.

The purpose of the GORE CARDIOFORM Septal Occluder (GSO Device) post-approval study is to assess the safety and effectiveness of GSO device as observed in the REDUCE pivotal IDE study, and to evaluate the quality of the operator education and training and transferability of trial experience to a post-market setting.

The purpose of this study is to compare a usual treatment alone to using MEDI4736 (durvalumab) plus the usual treatment. The study approach could shrink your cancer. But, it could also cause side effects, which are described in the risks section below. MEDI4736 (durvalumab) is a type of immunotherapy drug that is already approved by the FDA for use in urothelial cancer. But, most of the time it is not used until platinum-containing chemotherapy, such as cisplatin, stops working for your cancer. This study will help the study doctors find out if this different approach is better than the usual approach. To decide if it is better, the study doctors will be looking at two main factors. They will be investigating if the study approach will increase the number of patients whose cancer is shrunk significantly after surgery. They will also be investigating if the study approach increases the number of patients who do not have the cancer come back or get worse.

This study wants to find out if a blood test can help doctors decide which patients need more treatment after surgical removal of the bladder, kidney, ureter, or urethra. This blood test looks for small pieces of cancer DNA, called ctDNA, in the blood. If ctDNA is found, it means some cancer cells may still be in the body. The trial will give some patients an extra medicine, called immunotherapy, to help their immune system find and kill any remaining cancer. This will help doctors learn if using the blood test to guide treatment will help patients live longer without their cancer coming back.